![]() ![]() Three thousand four hundred and sixteen (3416) blood donors' data from Armed Forces Hospital blood bank were collected. The results were compared with other populations. The data were reviewed and calculations performed to determine ABO and Rh (D) phenotypes, allele frequencies and genotypes estimation. This retrospective study concerning ABO and Rh (D) blood groups of a small section of the Omani population was undertaken between January 2017 and December 2017. Due to frequencies variation throughout the world and lack of study in Oman, this propelled us to determine the phenotypes and estimate the genetic variability of ABO and Rh (D) blood groups in the Omani population. Oman is a genetically admixed population country consisting of African, Caucasian and Asian ancestries. The distribution may also vary across country areas due to different ethnic groups. There is no significant difference in the renal function status of blood donors with SCT and normal haemoglobin genotype.įrequencies of ABO and Rh (D) groups vary throughout the world due to ethnic diversity. The prevalence of sickle cell trait among Nigerian blood donors is high. ![]() There was no significant difference in the mean eGFR between subjects with haemoglobin AA and AS (mean difference 5.3, p = 0.265, 95%CI = -4.07 to 14.60). ![]() The mean eGFR for subjects with haemoglobin AA and AS were 105.2☑8.6ml/min/1.73m2 and 99.9 ± 21.2ml/min/1.73m2 respectively (p value = 0.270). Eighty one (79.4%) and 21 (20.6%) subjects had haemoglobin AA and AS genotypes respectively. Their haemoglobin genotype and, estimated glomerular filtration rates were determined. To determine the prevalence of haemoglobin AS and its association to renal function, if any.Īpparently healthy donors were studied between February and December 2018. Prospective blood donors are routinely screened for blood borne infections but medical illnesses and haemoglobin genotype are overlooked despite a high prevalence of haemoglobin AS among Nigerian donors. Information about allele frequencies of blood groups among different populations worldwide will help in framing policy decisions to face future challenges in healthcare services. Conclusions The distribution of the two major blood group systems namely ABO and Rh (D) systems show considerable heterogeneity in different populations of the world. The allele frequencies of ABO and Rh (D) blood groups were 0.1628 for IA, 0.2177 for IB, 0.6259 for IO, 0.7991 for ID, and 0.2009 for Id. ![]() A majority (95.96%) of the blood donors were Rh (D) positive. The phenotypic frequency of blood group O (39.17%) was the highest and that of blood group AB (7.88%) was the least. The most common blood group was O positive (37.67%) while AB negative (0.18%) was the least common blood group. Results Out of total a of 7598 blood donors, 7576 (99.71%) were males and 22 (0.29%) were females. Allele frequency of the blood group genes was calculated based on Hardy-Weinberg equilibrium. ABO and Rh (D) blood grouping of all the blood donors were carried out by tube agglutination method. Methods This was a retrospective observational study carried out in the blood bank of Karpaga Vinayaga Institute of Medical Sciences and Research Centre from January 2015 to December 2021. The objective of the study is to estimate the distribution of ABO & Rh (D) blood groups among all the blood donors in a tertiary care hospital in Chengalpattu district of Tamilnadu in South India and to determine their allele frequencies. Introduction The distribution of ABO and Rh (D) blood groups and their allele frequencies vary from one population to another worldwide. ![]()
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